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Research Infrastructure Registry in Cyprus
HomeDatabase  /  Biological and Medical Sciences  /  Biological/Biomedical Engineering and Biotechnology/Nanotechnology Research Facilities  /  Biorheology Lab

Biorheology Lab

GENERAL INFORMATION

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  Biorheology Lab
Cyprus University of Technology
Cyprus University of Technology
  Biological/Biomedical Engineering and Biotechnology/Nanotechnology Research Facilities,  Biorheology,  Rheology,  Mechanical Engineering Facilities,  Micro and Nanotechnology Facilities
Description and purpose of the Research Infrastructure

Our research interests include rheology and fluid mechanics of blood and other complex fluids and biofuids. Our laboratory is equipped with the necessary instruments for examining the rheology, structure, the mechanical properties of biofluid constituents, and the flow behaviour of such fluids in the microscale. The methods and techniques used in the laboratory include rheology, rheometry and optical rheology,  microfluidics and velocimetry. The results produced in the laboratory help to elucidate fundamental mechanisms, phenomena and bio-processes, as well as to find applications in areas such as diagnostics and treatment for issues of the circulatory and microcirculatory system.

Research Infrastructure Policy

Please click the link below to read the Open Access Policy for the Research Infrastructure:

CUT Open Access Policy

USEFUL FIGURES

Personnel

4

Personnel

Male

60%

Male

Female

40%

Female

Publications

36

Publications

ACCESS TO INFRASTRUCTURE

  • Academia
  • Industry

CONTACT INFO

Address:  30 Arch. Kyprianos Street

Postal Code:  3036

City:  Limassol

Website:  https://web.cut.ac.cy/biorheology/

Head of RI:  Efstathios Kaliviotis

Contact Person of RI:  Efstathios Kaliviotis   |  +357 25002289

INFORMATION OF INSTRUMENTATION OPERATING IN THE INFRASTRUCTURE

Advanced Rheometer Anton-Paar MCR702e
  • Name:  Advanced Rheometer Anton-Paar MCR702e
  • Description:  The Anton Paar MCR 702e MultiDrive is a high-end, modular rheometer designed for advanced rheological and dynamic mechanical characterization of a wide range of materials, from low-viscosity liquids to highly viscoelastic materials and solids. Its distinctive dual-drive configuration allows operation with either one or two independently controlled EC motors, enabling Combined Motor Transducer (CMT), Separate Motor Transducer (SMT), counter-rotation, and counter-oscillation measurement modes.
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
Supports highly precise rotational and oscillatory measurements, transient testing, and sophisticated investigations of material structure and flow behaviour. The instrument can also be equipped with a linear drive for dynamic mechanical analysis (DMA), including tension, compression, and bending measurements, as well as creep, relaxation, and thermomechanical analysis. Its modular architecture accommodates numerous measuring geometries, temperature-control systems, and specialized accessories, making the MCR 702e particularly suitable for demanding research and development applications in polymers, composites, suspensions, gels, and other complex materials.
Year:  2023
Funding Source: 
  • National
  • EU

Available for access
by external users

Elveflow Dry Film Microchannel Fibrication system
  • Name:  Elveflow Dry Film Microchannel Fibrication system
  • Description:  The Elveflow Dry Film Fabrication System is a laboratory solution designed for the rapid and reliable fabrication of microfluidic devices using dry-film photoresist technology. The system supports the preparation of high-quality microstructured molds and microfluidic patterns without requiring conventional cleanroom-based photolithography, making it particularly suitable for prototyping and research applications.
  • Units:  1
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
Dry-film photoresist is laminated onto a substrate and subsequently patterned through controlled UV exposure using a photomask, followed by development to obtain the desired microscale structures. These structures can be used directly or as molds for the fabrication of polymeric microfluidic devices, including PDMS-based chips. The approach provides good control over channel dimensions and enables reproducible fabrication while considerably simplifying the equipment and processing requirements associated with traditional microfabrication. The Elveflow system is therefore well suited to research laboratories developing lab-on-a-chip, organ-on-chip, droplet microfluidic, cell-culture, and other microscale fluid-handling devices.
Year:  2025
Funding Source: 
  • National
  • EU

Available for access
by external users

Optical Rheology Linkam CSS450 systems
  • Name:  Optical Rheology Linkam CSS450 systems
  • Description:  The Linkam CSS450 Optical Shearing System is a specialized temperature-controlled shear stage designed for the direct microscopic observation and characterization of materials while subjected to precisely controlled shear deformation. The system consists of two parallel optical windows, with the sample positioned between them, enabling controlled rotational shear to be applied while changes in the material’s microstructure are monitored in real time using optical microscopy. It is particularly suitable for investigating the relationship between shear conditions, temperature, and structural evolution in complex materials such as polymers, liquid crystals, emulsions, suspensions, gels, and biological or soft-matter systems.
  • Units:  1
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
The CSS450 enables researchers to study phenomena including flow-induced orientation, phase transitions, crystallization, deformation, and structural recovery under controlled experimental conditions. Its combination of accurate shear and temperature control with simultaneous optical visualization makes it a valuable research tool for rheo-optical studies, materials characterization, polymer science, soft-matter research, and the development of advanced functional materials.
Year:  2014
Funding Source: 
  • Own

Available for access
by external users

Red blood cell aggregometer and Cytometer (Deformability) Rheoscan A200 and D300
  • Name:  Red blood cell aggregometer and Cytometer (Deformability) Rheoscan A200 and D300
  • Description:  The RheoScan AnD300 (Aggregation and Deformability Analyzer) is a specialized analytical instrument designed for the quantitative assessment of red blood cell (RBC) aggregation and deformability, two important parameters of blood rheology and microcirculatory function. The system provides rapid and reproducible measurements using small-volume blood samples and controlled flow conditions.
  • Units:  1
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
RBC aggregation analysis evaluates the tendency of erythrocytes to form reversible aggregates under low-shear or stagnant conditions, while deformability measurements assess the ability of individual red blood cells to change shape when exposed to mechanical and shear stresses. These properties strongly influence blood viscosity and the capacity of erythrocytes to pass through small vessels and capillaries. By combining both measurements in a single analytical platform, the AnD300 provides comprehensive information on the rheological and mechanical behaviour of red blood cells. It is particularly suitable for hemorheology, microcirculation, biomedical research, clinical research, and studies investigating blood-related physiological or pathological changes.
Year:  2017
Funding Source: 
  • National

Available for access
by external users

ROTEM thromboelastography system
  • Name:  ROTEM thromboelastography system
  • Description:  The ROTEM (Rotational Thromboelastometry) System is an advanced diagnostic and research instrument designed for the real-time assessment of the viscoelastic properties of whole blood during clot formation and dissolution. Unlike conventional coagulation tests that evaluate isolated stages of the coagulation cascade, ROTEM provides a dynamic and comprehensive characterization of haemostasis, from the initiation and propagation of clot formation to maximum clot strength and subsequent fibrinolysis.
  • Units:  1
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
The system measures the mechanical properties of the developing blood clot through rotational thromboelastometry and generates characteristic curves from which parameters related to coagulation time, clot formation kinetics, clot firmness, platelet contribution, fibrinogen function, and fibrinolytic activity can be derived. Different assay configurations allow specific components of the haemostatic process to be investigated. The system is widely used in clinical and biomedical research involving coagulation disorders, haemostasis, thrombosis, trauma, cardiovascular conditions, surgery, transfusion medicine, and the evaluation of therapeutic interventions affecting blood coagulation.
Year:  2023
Funding Source: 
  • National
  • EU

Available for access
by external users

Elvesys Microfluidics system
  • Name:  Elvesys Microfluidics system
  • Description:  The Elveflow Microfluidic Flow Control System is a high-precision pressure-driven platform designed for accurate and dynamic control of fluid flow in microfluidic experiments, including Particle Image Velocimetry (PIV) applications. The system is based on the OB1 pressure controller, operating with pressure and flow sensing capabilities in the range of approximately −1 to +1 bar, enabling rapid and stable regulation of flow through microchannels. Integrated pressure and mass-flow sensors provide real-time monitoring and feedback control, allowing precise adjustment of experimental flow conditions and highly reproducible flow protocols. The system is combined with the MUX Distributor, which enables automated fluid routing, switching, and distribution between multiple reservoirs and microfluidic channels.
  • Units:  1
  • Hosting Laboratory / Department:  Biorheology Lab / Department of Mechanical Engineering and Materials Science and Engineering
Brief description of the utilization of the instrument:
This configuration is particularly suitable for μPIV experiments requiring well-controlled and repeatable velocity and shear conditions. It supports advanced studies in microfluidics, biofluid mechanics, haemodynamics and haemorheology, including investigations of blood and other complex biological fluids within microchannels and microvascular models.
Year:  2022
Funding Source: 
  • National
  • EU

Available for access
by external users